The best Side of ceesdekker
The best Side of ceesdekker
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Halfway by means of his vocation, Cees Dekker reinvented himself. Soon after many years of hardcore physics, he shifted his concentration to ‘nanobiology’ in the transform in the millennium. A time period he coined himself, as being a subject of reality.
Our team scientific tests bacterial mobile division and it is aiming to constitute a ‘base up biology’ in synthetic cells that may autonomously divide. Our primary desire lies in mobile division, chromatin construction, and spatial Handle.
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I am able to barely picture how I, being a geneticist, would be capable to find out basic physics, let alone contend at the highest. How did you go about this?
We create point-of-treatment diagnostics examination of neglected tropical ailments inside resource-confined options, depending on Crspr/Cas9 detecting of pathogen’s DNA in physique fluids.
The coiled-coil on the human Rad50 DNA restore protein incorporates precise segments of improved adaptability
Considering the fact that 2000 he moved to one-molecule biophysics and nanobiology, with investigation from DNA supercoiling scientific studies of nucleosomes and DNA restore proteins to DNA translocation through nanopores. A short while ago his exploration has focused on researching mobile division with germs on chip, while his best curiosity is within the way of noticing synthetic cells.
Atomic power microscopy reveals that vaccinia topoisomerase IB generates filaments on DNA inside a cooperative trend
‘You should not just think of the inquiries of tomorrow, and also look at the issues with the working day soon after tomorrow’
1). The existing–voltage curves showed sizeable modulations with gate voltage, even at area temperature, which was consistent with band bending in the ~0.six eV bandgap semiconducting nanotube. These knowledge also confirmed that the conductance may very well be modulated by six orders of magnitude by altering the gate voltage. The final results of this operate — a home-temperature transistor made out of only one carbon nanotube molecule — had been posted in Nature in May possibly 1998.
Screening pseudotopological and nontopological models for SMC-driven DNA loop extrusion versus roadblock-traversal experiments
Numerous new https://www.ceesdekker.net phenomena were being uncovered, and he and his study team proven a number one placement Within this subject of analysis. Dekker and his research team found new physics of nanotubes together with explored the feasibility of molecular electronics. In 1998, they had been the main to develop a transistor according to only one nanotube molecule.
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It was an extremely attention-grabbing time, in the course of which I gained a lot of help from Delft College of Technological know-how, the place I had been a professor at the time, and I commenced various collaborations with molecular biologists. That helped me discover a good deal.’